JPKD  
(formerly JavaPK for Desktop) a clinical pharma-cokinetic tool using Bayesian estimation, Sauchuk-Zaske method for aminoglycoside/ vancomycin, and Chiou method for theophylline; includes 15 commonly monitored drugs. User defined tdm model is allowed. (Win XP/vista,  Mac OS X & Linux-PC)
PKfit
a data analysis tool for individual pharmaco-kinetics created on 2005 for R (.avi demo, please use full-screen mode to view. Press F11 with IE or Firefox)
ivivc 
a package for the in-vitro and in-vivo correlation (ivivc) modeling and model validation; created on 2008 for R and has been released on April 11, 2008. flash demo

bear
a package for BE/BA data analysis for R using noncompartmental analysis (NCA), ANOVA, linear mixed effect model (lme from nlme R package) and some outlier detection analysis.  The BE study design can be an 2x2x2 ABE, TTT, balanced or imbalanced crossover, single-dose designed, or replicate crossover study (2-trt x 2-sqe x 3-pr, 2x2x4... 2x2x6). Bear was first released on July, 10, 2008. (demo was created with v1.0.0)
tdm
a tool for therapeutic drug monitoring created on 2006 for R using Brug to call WinBUGS to estimate PK/PD parameters (.avi demo, please use full-screen mode to view. Press F11 with IE or Firefox)
stab
a package for data analysis of drug stability based on the the ICH guideline Q1E Evaluation
of Stability Data (such as estimation of shelf-life from a 3-batch or more drug stability profiles.) for R